Views:89 Author:Site Editor Publish Time: 2021-08-27 Origin:Site
Coenzyme Q10 (CAS NO.303-98-0 ) is a fat-soluble antioxidant, which can activate the nutrition of human cells and cellular energy, and has the functions of improving human immunity, enhancing antioxidation, delaying ageing and enhancing human vitality.
It is widely used in medicine for cardiovascular diseases and is widely used in nutritional supplements and food additives at home and abroad.
Coenzyme Q10, taken alone or together with vitamin E, is a powerful antioxidant that slows down skin ageing and is used in anti-ageing cosmetics. In addition, it plays an important role in strengthening the body's production of energy (adenosine triphosphate ATP), which strengthens the heart and relieves hypoxia. Coenzyme Q10 is found in 50 to 75 million cells throughout the body and is particularly abundant in the heart, lungs, liver, kidneys, spleen, pancreas and adrenal glands.
The Function of Coenzyme Q10
1.Coenzyme Q10 Is An Important Coenzyme in the Body
Coenzymes are a class of organic small molecules that can transfer chemical groups from one enzyme to another, which can be more loosely bound to enzymes and are important components of enzyme activity. Coenzyme Q10 is an important coenzyme in the body, and is an important hydrogen transmitter in the respiratory chain of biological cells, participating in the process of oxidative phosphorylation and ATP production, and regulating the cellular redox environment. In the respiratory chain, coenzyme Q10 is a coenzyme that is not tightly bound to proteins, which enables it to act as a special flexible carrier between flavoproteins and cytochromes; in addition, the hydroxyl substituent of benzoquinone in its quinone ring makes it inclined to polarity, while the polyisoprene side chain in its structure gives it low free energy in a hydrophobic environment and can diffuse rapidly in the inner mitochondrial membrane. Coenzyme Q10 receives hydrogen from complex I and complex II, release protons into the mitochondrial matrix, and electrons are transferred to cytochromes, through which process oxidative phosphorylation and active electron transfer are promoted, resulting in the formation of ATP, the main substance of energy storage in the organism. coenzyme Q10 is often consumed in the reactions it helps, but coenzyme Q10 can be produced again and its concentration in the cell is maintained at a stable level. The body's ability to synthesize coenzyme Q10 gradually decreases with age and the effects of the disease. Coenzyme Q10, like many vitamins and their derivatives, such as riboflavin, thiamin and coenzymes such as folic acid, can only be obtained primarily through dietary supplementation.
2.Coenzyme Q10 Is A Free Radical Scavenger in the Body
Why do humans age? A free radical theory of ageing suggests that the main cause of ageing is the oxidative damage caused by free radicals to biological macromolecules (nucleic acids, lipids, proteins, etc.) in cells, which accumulates with age and thus damages cellular functions, leading to the decline or loss of cellular functions and eventually causing the ageing of the body. Mitochondria (especially the damaged mitochondria) are the main organelle for free radical generation in cells, while the mitochondria themselves are rich in a variety of enzymes, structural proteins, membrane lipids and nucleic acids, etc. are also the direct targets of oxidants such as reactive oxygen species, and damage to mitochondrial structure and reduced enzyme activity in turn further aggravate mitochondrial damage, resulting in impaired cellular energy metabolism and loss of cellular function. Coenzyme Q10 can prevent lipid and protein peroxidation, scavenge free radicals, significantly reduce mitochondrial oxygen consumption, reduce cellular adenosine triphosphate consumption, maintain the integrity of the cellular mitochondrial structure, prevent cellular oedema, cell membrane rupture, as well as mitochondrial lysis and disordered arrangement of muscle fibres, Coenzyme Q10 can also strengthen the inner cell membrane against damage from external oxidative factors through redox structural transformation, and is Coenzyme Q10 is the only naturally occurring fat-soluble antioxidant that can be regenerated in the human body.
3.Coenzyme Q10 Is An Activator of Cellular Metabolism
Metabolism is a fundamental characteristic of human life activity. Metabolism includes material metabolism and energy metabolism. Coenzyme Q10 can provide or remove oxygen in living organisms, and energy metabolism in living organisms is mainly carried out in mitochondria, which generates 95% of the total energy in the human body, and coenzyme Q10 exists on the inner membrane of mitochondria. Coenzyme Q10 is also an auxiliary component of several important enzymes in the mitochondrial oxidative phosphorylation reaction, and can prevent the reduction of substances required for ATP anabolism; Coenzyme Q10 is a metabolic activator, activating cellular respiration, playing a very important role in cellular energy generation and enhancing the vitality of organisms.